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Different effects of NK cells and NK-derived soluble factors on cell lines derived from primary or metastatic pancreatic cancers

Natural killer (NK) cells are cytotoxic lymphoid cells that play a key role in defenses against tumors. However, their function may be severely impaired in patients with pancreatic adenocarcinoma (PA). Indeed, PA cells release soluble factors, thereby generating an immunosuppressive environment that...

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Detalles Bibliográficos
Autores principales: Fiore, Piera Filomena, Di Pace, Anna Laura, Conti, Libenzio Adrian, Tumino, Nicola, Besi, Francesca, Scaglione, Silvia, Munari, Enrico, Moretta, Lorenzo, Vacca, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198856/
https://www.ncbi.nlm.nih.gov/pubmed/36451048
http://dx.doi.org/10.1007/s00262-022-03340-z