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Different effects of NK cells and NK-derived soluble factors on cell lines derived from primary or metastatic pancreatic cancers
Natural killer (NK) cells are cytotoxic lymphoid cells that play a key role in defenses against tumors. However, their function may be severely impaired in patients with pancreatic adenocarcinoma (PA). Indeed, PA cells release soluble factors, thereby generating an immunosuppressive environment that...
Autores principales: | Fiore, Piera Filomena, Di Pace, Anna Laura, Conti, Libenzio Adrian, Tumino, Nicola, Besi, Francesca, Scaglione, Silvia, Munari, Enrico, Moretta, Lorenzo, Vacca, Paola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198856/ https://www.ncbi.nlm.nih.gov/pubmed/36451048 http://dx.doi.org/10.1007/s00262-022-03340-z |
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