Biased activation of the receptor tyrosine kinase HER2

HER2 belongs to the ErbB sub-family of receptor tyrosine kinases and regulates cellular proliferation and growth. Different from other ErbB receptors, HER2 has no known ligand. Activation occurs through heterodimerization with other ErbB receptors and their cognate ligands. This suggests several pos...

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Detalles Bibliográficos
Autores principales: Catapano, Claudia, Rahm, Johanna V., Omer, Marjan, Teodori, Laura, Kjems, Jørgen, Dietz, Marina S., Heilemann, Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198881/
https://www.ncbi.nlm.nih.gov/pubmed/37208479
http://dx.doi.org/10.1007/s00018-023-04806-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198881/
https://www.ncbi.nlm.nih.gov/pubmed/37208479
http://dx.doi.org/10.1007/s00018-023-04806-8

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