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Inhibition of importin-7 attenuates ventilator-induced lung injury by targeting nuclear translocation of p38
BACKGROUND: The ability of p38 to phosphorylate substrates in the nucleus and the role of nuclear p38 in the regulation of inflammation have focused attention on the subcellular localization of the kinase. Although it is clear that p38 shuttles to the nucleus upon stimulation, the mechanisms that re...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198890/ https://www.ncbi.nlm.nih.gov/pubmed/37004548 http://dx.doi.org/10.1007/s00011-023-01727-x |