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Cxcr3 constrains pancreatic cancer dissemination through instructing T cell fate

Pancreatic ductal adenocarcinoma (PDA) is a lethal and metastatic malignancy resistant to therapy. Elucidating how pancreatic tumor-specific T cells differentiate and are maintained in vivo could inform novel therapeutic avenues to promote T cell antitumor activity. Here, we show that the spleen is...

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Detalles Bibliográficos
Autores principales: Burrack, Adam L., Spartz, Ellen J., Rollins, Meagan R., Miller, Ebony A., Firulyova, Maria, Cruz, Eduardo, Goldberg, Michael F., Wang, Iris X., Nanda, Hezkiel, Shen, Steven, Zaitsev, Konstantin, Stromnes, Ingunn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198906/
https://www.ncbi.nlm.nih.gov/pubmed/36472588
http://dx.doi.org/10.1007/s00262-022-03338-7