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Cxcr3 constrains pancreatic cancer dissemination through instructing T cell fate
Pancreatic ductal adenocarcinoma (PDA) is a lethal and metastatic malignancy resistant to therapy. Elucidating how pancreatic tumor-specific T cells differentiate and are maintained in vivo could inform novel therapeutic avenues to promote T cell antitumor activity. Here, we show that the spleen is...
Autores principales: | Burrack, Adam L., Spartz, Ellen J., Rollins, Meagan R., Miller, Ebony A., Firulyova, Maria, Cruz, Eduardo, Goldberg, Michael F., Wang, Iris X., Nanda, Hezkiel, Shen, Steven, Zaitsev, Konstantin, Stromnes, Ingunn M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198906/ https://www.ncbi.nlm.nih.gov/pubmed/36472588 http://dx.doi.org/10.1007/s00262-022-03338-7 |
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