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Oral Capecitabine Exposures and Use of Uridine Triacetate: A 20-Year Retrospective Analysis

BACKGROUND AND OBJECTIVES: Capecitabine is an oral prodrug of 5-fluorouracil. Toxicity can occur during therapy as well as acutely with overdose and particular genetic susceptibilities. Uridine triacetate is an effective antidote if given within 96 h of exposure. This study seeks to characterize acc...

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Detalles Bibliográficos
Autores principales: Seltzer, Justin A., Friedman, Nathan A., Hardin, Jeremy, Galust, Henrik, Cantrell, F. Lee, Minns, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198921/
https://www.ncbi.nlm.nih.gov/pubmed/37072662
http://dx.doi.org/10.1007/s40261-023-01268-5