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Computational design of dynamic receptor—peptide signaling complexes applied to chemotaxis

Engineering protein biosensors that sensitively respond to specific biomolecules by triggering precise cellular responses is a major goal of diagnostics and synthetic cell biology. Previous biosensor designs have largely relied on binding structurally well-defined molecules. In contrast, approaches...

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Detalles Bibliográficos
Autores principales: Jefferson, Robert E., Oggier, Aurélien, Füglistaler, Andreas, Camviel, Nicolas, Hijazi, Mahdi, Villarreal, Ana Rico, Arber, Caroline, Barth, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198977/
https://www.ncbi.nlm.nih.gov/pubmed/37208363
http://dx.doi.org/10.1038/s41467-023-38491-9