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Computational design of dynamic receptor—peptide signaling complexes applied to chemotaxis
Engineering protein biosensors that sensitively respond to specific biomolecules by triggering precise cellular responses is a major goal of diagnostics and synthetic cell biology. Previous biosensor designs have largely relied on binding structurally well-defined molecules. In contrast, approaches...
Autores principales: | Jefferson, Robert E., Oggier, Aurélien, Füglistaler, Andreas, Camviel, Nicolas, Hijazi, Mahdi, Villarreal, Ana Rico, Arber, Caroline, Barth, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198977/ https://www.ncbi.nlm.nih.gov/pubmed/37208363 http://dx.doi.org/10.1038/s41467-023-38491-9 |
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