Baseline P2Y12 reactivity, kidney function, and CYP2C19 genotype determine clopidogrel responsiveness in acute stroke

Clopidogrel is the most-widely used platelet P2Y12-inhibitor for secondary-prevention of ischemic stroke. Platelet P2Y12 reactivity before and after inhibitors can be measured with blood sampling by commercialized system. We aimed to evaluate (1) whether high-on-clopidogrel platelet P2Y12 reactivity...

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Detalles Bibliográficos
Autores principales: Lee, Yi-Chung, Liao, Yi-Chu, Lin, Chun-Jen, Chung, Chih-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198986/
https://www.ncbi.nlm.nih.gov/pubmed/37208337
http://dx.doi.org/10.1038/s41598-023-34481-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198986/
https://www.ncbi.nlm.nih.gov/pubmed/37208337
http://dx.doi.org/10.1038/s41598-023-34481-5

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