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Impaired expression of metallothioneins contributes to allergen-induced inflammation in patients with atopic dermatitis

Regulation of cutaneous immunity is severely compromised in inflammatory skin disease. To investigate the molecular crosstalk underpinning tolerance versus inflammation in atopic dermatitis, we utilise a human in vivo allergen challenge study, exposing atopic dermatitis patients to house dust mite....

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Detalles Bibliográficos
Autores principales: Sirvent, Sofia, Vallejo, Andres F., Corden, Emma, Teo, Ying, Davies, James, Clayton, Kalum, Seaby, Eleanor G., Lai, Chester, Ennis, Sarah, Alyami, Rfeef, Douilhet, Gemma, Dean, Lareb S. N., Loxham, Matthew, Horswill, Sarah, Healy, Eugene, Roberts, Graham, Hall, Nigel J., Friedmann, Peter S., Singh, Harinder, Bennett, Clare L., Ardern-Jones, Michael R, Polak, Marta E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199008/
https://www.ncbi.nlm.nih.gov/pubmed/37208336
http://dx.doi.org/10.1038/s41467-023-38588-1