Characterisation of IL-23 receptor antagonists and disease relevant mutants using fluorescent probes

Association of single nucleotide polymorphisms in the IL-23 receptor with several auto-inflammatory diseases, led to the heterodimeric receptor and its cytokine-ligand IL-23, becoming important drug targets. Successful antibody-based therapies directed against the cytokine have been licenced and a c...

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Detalles Bibliográficos
Autores principales: Lay, Charles S., Isidro-Llobet, Albert, Kilpatrick, Laura E., Craggs, Peter D., Hill, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199020/
https://www.ncbi.nlm.nih.gov/pubmed/37208328
http://dx.doi.org/10.1038/s41467-023-38541-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199020/
https://www.ncbi.nlm.nih.gov/pubmed/37208328
http://dx.doi.org/10.1038/s41467-023-38541-2

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