Noradrenergic stimulation of α(1) adrenoceptors in the medial prefrontal cortex mediates acute stress-induced facilitation of seizures in mice

Stress is one of the critical facilitators for seizure induction in patients with epilepsy. However, the neural mechanisms underlying this facilitation remain poorly understood. Here, we investigated whether noradrenaline (NA) transmission enhanced by stress exposure facilitates the induction of med...

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Detalles Bibliográficos
Autores principales: Niitani, Kazuhei, Ito, Shiho, Wada, Shintaro, Izumi, Shoma, Nishitani, Naoya, Deyama, Satoshi, Kaneda, Katsuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199052/
https://www.ncbi.nlm.nih.gov/pubmed/37208473
http://dx.doi.org/10.1038/s41598-023-35242-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199052/
https://www.ncbi.nlm.nih.gov/pubmed/37208473
http://dx.doi.org/10.1038/s41598-023-35242-0

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