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Evaluation of rosuvastatin-induced QT prolongation risk using real-world data, in vitro cardiomyocyte studies, and mortality assessment

Drug-induced QT prolongation is attributed to several mechanisms, including hERG channel blockage. However, the risks, mechanisms, and the effects of rosuvastatin-induced QT prolongation remain unclear. Therefore, this study assessed the risk of rosuvastatin-induced QT prolongation using (1) real-wo...

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Detalles Bibliográficos
Autores principales: Koo, Yeryung, Hyun, Sung-Ae, Choi, Byung Jin, Kim, Yujeong, Kim, Tae Young, Lim, Hong-Seok, Seo, Joung-Wook, Yoon, Dukyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199059/
https://www.ncbi.nlm.nih.gov/pubmed/37208484
http://dx.doi.org/10.1038/s41598-023-35146-z