N-Terminomic Changes in Neurons During Excitotoxicity Reveal Proteolytic Events Associated With Synaptic Dysfunctions and Potential Targets for Neuroprotection

Excitotoxicity, a neuronal death process in neurological disorders such as stroke, is initiated by the overstimulation of ionotropic glutamate receptors. Although dysregulation of proteolytic signaling networks is critical for excitotoxicity, the identity of affected proteins and mechanisms by which...

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Detalles Bibliográficos
Autores principales: Ameen, S. Sadia, Griem-Krey, Nane, Dufour, Antoine, Hossain, M. Iqbal, Hoque, Ashfaqul, Sturgeon, Sharelle, Nandurkar, Harshal, Draxler, Dominik F., Medcalf, Robert L., Kamaruddin, Mohd Aizuddin, Lucet, Isabelle S., Leeming, Michael G., Liu, Dazhi, Dhillon, Amardeep, Lim, Jet Phey, Basheer, Faiza, Zhu, Hong-Jian, Bokhari, Laita, Roulston, Carli L., Paradkar, Prasad N., Kleifeld, Oded, Clarkson, Andrew N., Wellendorph, Petrine, Ciccotosto, Giuseppe D., Williamson, Nicholas A., Ang, Ching-Seng, Cheng, Heung-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199228/
https://www.ncbi.nlm.nih.gov/pubmed/37030595
http://dx.doi.org/10.1016/j.mcpro.2023.100543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199228/
https://www.ncbi.nlm.nih.gov/pubmed/37030595
http://dx.doi.org/10.1016/j.mcpro.2023.100543

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