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Reactive sulfur species disaggregate the SQSTM1/p62-based aggresome-like induced structures via the HSP70 induction and prevent parthanatos

Reactive sulfur species (RSS) have emerged as key regulators of protein quality control. However, the mechanisms by which RSS contribute to cellular processes are not fully understood. In this study, we identified a novel function of RSS in preventing parthanatos, a nonapoptotic form of cell death t...

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Detalles Bibliográficos
Autores principales: Yamada, Yutaro, Noguchi, Takuya, Suzuki, Midori, Yamada, Mayuka, Hirata, Yusuke, Matsuzawa, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199230/
https://www.ncbi.nlm.nih.gov/pubmed/37060999
http://dx.doi.org/10.1016/j.jbc.2023.104710