The Antipsychotic Drug Haldol Modulates IQGAP1-Signaling and Inhibits Cell Proliferation in Triple Negative Breast Cancer Cell Lines

The signaling scaffold oncoprotein IQGAP1 was identified as a classification and therapeutic biomarker in triple negative breast cancer (TNBC) cell lines. Here, we report that the antipsychotic drug Haldol induces novel protein-protein interactions with IQGAP1 and inhibits cell proliferation in TNBC...

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Detalles Bibliográficos
Autores principales: Iyer, Varun J., Osman, Mahasin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2023
Materias:
New Finding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199339/
https://www.ncbi.nlm.nih.gov/pubmed/37215640
http://dx.doi.org/10.17912/micropub.biology.000823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199339/
https://www.ncbi.nlm.nih.gov/pubmed/37215640
http://dx.doi.org/10.17912/micropub.biology.000823

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