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Effect of troxerutin on the expression of genes regulating mitochondrial biogenesis and microRNA-140 in doxorubicin-induced testicular toxicity

BACKGROUND: Application of doxorubicin (DOX) in cancer patients is limited due to its dose-dependent toxicity to nontarget tissues such as testis and subsequent infertility. Due to limitation of our knowledge about the mechanisms of DOX toxicity in the reproductive system, reduction of DOX-induced t...

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Detalles Bibliográficos
Autores principales: Mokhtari, Behnaz, Abdi, Arezou, Athari, Seyed Zanyar, Nozad-Charoudeh, Hojjatollah, Alihemmati, Alireza, Badalzadeh, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199378/
https://www.ncbi.nlm.nih.gov/pubmed/37213461
http://dx.doi.org/10.4103/jrms.jrms_120_22