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Investigation of the relationship between ergocristinine and vascular receptors

Ergot alkaloids are secondary metabolites that exist in two configurations, the C-8-R-isomer (R-epimer), and the C-8-S-isomer (S-epimer). Toxic effects of ergot, such as vasoconstriction, have been primarily attributed to the R-epimer bioactivity, as compared to the S-epimer. Recent studies demonstr...

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Detalles Bibliográficos
Autores principales: Cherewyk, Jensen E., Blakley, Barry R., Al-Dissi, Ahmad N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199403/
https://www.ncbi.nlm.nih.gov/pubmed/37213815
http://dx.doi.org/10.1016/j.toxrep.2023.05.005