Modeling Pkd1 gene-targeted strategies for correction of polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD) causes renal cysts and leads to end-stage renal disease in midlife due mainly to PKD1 gene mutations. Virtually no studies have explored gene therapeutic strategies for long-term effective treatment of PKD. Toward this aim, the severely cystic Pkd...

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Detalles Bibliográficos
Autores principales: Kurbegovic, Almira, Pacis, Rey Christian, Trudel, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199405/
https://www.ncbi.nlm.nih.gov/pubmed/37214311
http://dx.doi.org/10.1016/j.omtm.2023.03.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199405/
https://www.ncbi.nlm.nih.gov/pubmed/37214311
http://dx.doi.org/10.1016/j.omtm.2023.03.016

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