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LncRNA ZNF593-AS alleviates diabetic cardiomyopathy via suppressing IRF3 signaling pathway

Diabetes could directly induce cardiac injury, leading to cardiomyopathy. However, treatment strategies for diabetic cardiomyopathy remain limited. ZNF593-AS knockout and cardiomyocyte-specific transgenic mice were constructed. In addition, high-fat diet (HFD)-induced diabetic mouse model and db/db...

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Detalles Bibliográficos
Autores principales: Xie, Rong, Fan, Jiahui, Wen, Jianpei, Jin, Kunying, Zhan, Jiabing, Yuan, Shuai, Tang, Yuyan, Nie, Xiang, Wen, Zheng, Li, Huaping, Chen, Chen, Wang, Dao Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199406/
https://www.ncbi.nlm.nih.gov/pubmed/37215148
http://dx.doi.org/10.1016/j.omtn.2023.04.025