Neutral theory: applicability and neutrality of clinical study endpoints where a disease-specific instrument is available

BACKGROUND: There is a pressing need to improve the accuracy of rare disease clinical study endpoints. Neutral theory, first described here, can be used to assess the accuracy of endpoints and improve their selection in rare disease clinical studies, reducing the risk of patient misclassification. M...

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Detalles Bibliográficos
Autor principal: Jandhyala, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199426/
https://www.ncbi.nlm.nih.gov/pubmed/37210484
http://dx.doi.org/10.1186/s12874-023-01947-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199426/
https://www.ncbi.nlm.nih.gov/pubmed/37210484
http://dx.doi.org/10.1186/s12874-023-01947-z

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