Isoliensinine from Cissampelos pariera rhizomes exhibits potential gametocytocidal and anti-malarial activities against Plasmodium falciparum clinical isolates

BACKGROUND: The unmet demand for effective malaria transmission-blocking agents targeting the transmissible stages of Plasmodium necessitates intensive discovery efforts. In this study, a bioactive bisbenzylisoquinoline (BBIQ), isoliensinine, from Cissampelos pariera (Menispermaceae) rhizomes was id...

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Detalles Bibliográficos
Autores principales: Muema, Jackson M., Mutunga, James M., Obonyo, Meshack A., Getahun, Merid N., Mwakubambanya, Ramadhan S., Akala, Hoseah M., Cheruiyot, Agnes C., Yeda, Redemptah A., Juma, Dennis W., Andagalu, Ben, Johnson, Jaree L., Roth, Amanda L., Bargul, Joel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199507/
https://www.ncbi.nlm.nih.gov/pubmed/37208735
http://dx.doi.org/10.1186/s12936-023-04590-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199507/
https://www.ncbi.nlm.nih.gov/pubmed/37208735
http://dx.doi.org/10.1186/s12936-023-04590-7

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