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Retina-to-brain spreading of α-synuclein after intravitreal injection of preformed fibrils

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the aggregation of misfolded α-synuclein and progressive spreading of the aggregates from a few discrete regions to wider brain regions. Although PD has been classically considered a movement disorder, a large body of clinical...

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Detalles Bibliográficos
Autores principales: Pérez-Acuña, Dayana, Rhee, Ka Hyun, Shin, Soo Jean, Ahn, Jeeyun, Lee, Jee-Young, Lee, Seung-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199563/
https://www.ncbi.nlm.nih.gov/pubmed/37210559
http://dx.doi.org/10.1186/s40478-023-01575-0