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Retina-to-brain spreading of α-synuclein after intravitreal injection of preformed fibrils
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the aggregation of misfolded α-synuclein and progressive spreading of the aggregates from a few discrete regions to wider brain regions. Although PD has been classically considered a movement disorder, a large body of clinical...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199563/ https://www.ncbi.nlm.nih.gov/pubmed/37210559 http://dx.doi.org/10.1186/s40478-023-01575-0 |