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Evolocumab loaded Bio-Liposomes for efficient atherosclerosis therapy

PCSK9, which is closely related to atherosclerosis, is significantly expressed in vascular smooth muscle cells (VSMCs). Moreover, Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) mediated phenotypic transformation, abnormal proliferation, and migration of VSMCs play key roles in accelerating at...

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Detalles Bibliográficos
Autores principales: Li, Zhenxian, Zhu, Haimei, Liu, Hao, Liu, Dayue, Liu, Jianhe, Jiang, Jiazheng, Zhang, Yi, Qin, Zhang, Xu, Yijia, Peng, Yuan, Liu, Bin, Long, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199622/
https://www.ncbi.nlm.nih.gov/pubmed/37208681
http://dx.doi.org/10.1186/s12951-023-01904-4