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Serum metabolomic signatures of fatty acid oxidation defects differentiate host-response subphenotypes of acute respiratory distress syndrome

BACKGROUND: Fatty acid oxidation (FAO) defects have been implicated in experimental models of acute lung injury and associated with poor outcomes in critical illness. In this study, we examined acylcarnitine profiles and 3-methylhistidine as markers of FAO defects and skeletal muscle catabolism, res...

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Detalles Bibliográficos
Autores principales: Suber, Tomeka L., Wendell, Stacy G., Mullett, Steven J., Zuchelkowski, Benjamin, Bain, William, Kitsios, Georgios D., McVerry, Bryan J., Ray, Prabir, Ray, Anuradha, Mallampalli, Rama K., Zhang, Yingze, Shah, Faraaz, Nouraie, Seyed Mehdi, Lee, Janet S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199668/
https://www.ncbi.nlm.nih.gov/pubmed/37210531
http://dx.doi.org/10.1186/s12931-023-02447-w