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Serum metabolomic signatures of fatty acid oxidation defects differentiate host-response subphenotypes of acute respiratory distress syndrome
BACKGROUND: Fatty acid oxidation (FAO) defects have been implicated in experimental models of acute lung injury and associated with poor outcomes in critical illness. In this study, we examined acylcarnitine profiles and 3-methylhistidine as markers of FAO defects and skeletal muscle catabolism, res...
Autores principales: | Suber, Tomeka L., Wendell, Stacy G., Mullett, Steven J., Zuchelkowski, Benjamin, Bain, William, Kitsios, Georgios D., McVerry, Bryan J., Ray, Prabir, Ray, Anuradha, Mallampalli, Rama K., Zhang, Yingze, Shah, Faraaz, Nouraie, Seyed Mehdi, Lee, Janet S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199668/ https://www.ncbi.nlm.nih.gov/pubmed/37210531 http://dx.doi.org/10.1186/s12931-023-02447-w |
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