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Stability-Enhanced Ternary Solid Dispersions of Glyburide: Effect of Preparation Method on Physicochemical Properties

INTRODUCTION: Limited aqueous solubility and subsequent poor absorption and low bioavailability are the main challenges in oral drug delivery. Solid dispersion is a widely used formulation strategy to overcome this problem. Despite their efficiency, drug crystallization tendency and poor physical st...

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Detalles Bibliográficos
Autores principales: Barghi, Leila, Vekalati, Afshin, Jahangiri, Azin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199792/
https://www.ncbi.nlm.nih.gov/pubmed/37215486
http://dx.doi.org/10.1155/2023/2641153