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Fibroblast activation protein-targeted radionuclide therapy: background, opportunities, and challenges of first (pre)clinical studies

INTRODUCTION: Fibroblast activation protein (FAP) is highly overexpressed in stromal tissue of various cancers. While FAP has been recognized as a potential diagnostic or therapeutic cancer target for decades, the surge of radiolabeled FAP-targeting molecules has the potential to revolutionize its p...

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Detalles Bibliográficos
Autores principales: Privé, Bastiaan M., Boussihmad, Mohamed A., Timmermans, Bart, van Gemert, Willemijn A., Peters, Steffie M. B., Derks, Yvonne H. W., van Lith, Sanne A. M., Mehra, Niven, Nagarajah, James, Heskamp, Sandra, Westdorp, Harm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199876/
https://www.ncbi.nlm.nih.gov/pubmed/36813980
http://dx.doi.org/10.1007/s00259-023-06144-0