Cisplatin toxicity is counteracted by the activation of the p38/ATF-7 signaling pathway in post-mitotic C. elegans

Cisplatin kills proliferating cells via DNA damage but also has profound effects on post-mitotic cells in tumors, kidneys, and neurons. However, the effects of cisplatin on post-mitotic cells are still poorly understood. Among model systems, C. elegans adults are unique in having completely post-mit...

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Detalles Bibliográficos
Autores principales: Raj, Dorota, Kraish, Bashar, Martikainen, Jari, Podraza-Farhanieh, Agnieszka, Kao, Gautam, Naredi, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199892/
https://www.ncbi.nlm.nih.gov/pubmed/37210583
http://dx.doi.org/10.1038/s41467-023-38568-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199892/
https://www.ncbi.nlm.nih.gov/pubmed/37210583
http://dx.doi.org/10.1038/s41467-023-38568-5

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