Klotho prevents transforming growth factor-β2-induced senescent-like morphological changes in the retinal pigment epithelium

Degenerative changes of the retinal pigment epithelium (RPE) triggered by transforming growth factor-β2 (TGF-β2) and oxidative stress play a critical role in the progression of age-related macular degeneration (AMD). The expression of α-klotho, an antiaging protein, declines with age, increasing the...

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Detalles Bibliográficos
Autores principales: Jang, Ha Young, Kim, Soo-Jin, Park, Kyu-Sang, Kim, Jeong Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199917/
https://www.ncbi.nlm.nih.gov/pubmed/37210384
http://dx.doi.org/10.1038/s41419-023-05851-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199917/
https://www.ncbi.nlm.nih.gov/pubmed/37210384
http://dx.doi.org/10.1038/s41419-023-05851-8

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