Identification of a mycobacterial hydrazidase, an isoniazid-hydrolyzing enzyme

There exists decades-old evidence that some mycobacteria, including Mycobacterium avium and Mycobacterium smegmatis, produce hydrazidase, an enzyme that can hydrolyze the first-line antitubercular agent isoniazid. Despite its importance as a potential resistance factor, no studies have attempted to...

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Detalles Bibliográficos
Autores principales: Sakiyama, Arata, Saren, Chaogetu, Kaneko, Yukihiro, Oinuma, Ken-Ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199920/
https://www.ncbi.nlm.nih.gov/pubmed/37210419
http://dx.doi.org/10.1038/s41598-023-35213-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199920/
https://www.ncbi.nlm.nih.gov/pubmed/37210419
http://dx.doi.org/10.1038/s41598-023-35213-5

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