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Identification of a mycobacterial hydrazidase, an isoniazid-hydrolyzing enzyme
There exists decades-old evidence that some mycobacteria, including Mycobacterium avium and Mycobacterium smegmatis, produce hydrazidase, an enzyme that can hydrolyze the first-line antitubercular agent isoniazid. Despite its importance as a potential resistance factor, no studies have attempted to...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199920/ https://www.ncbi.nlm.nih.gov/pubmed/37210419 http://dx.doi.org/10.1038/s41598-023-35213-5 |