IL-17A-mediated mitochondrial dysfunction induces pyroptosis in colorectal cancer cells and promotes CD8 + T-cell tumour infiltration

BACKGROUND: Interleukin-17A (IL-17A), a proinflammatory cytokine primarily secreted by Th17 cells, γδT cells and natural killer T (NKT) cells, performs essential roles in the microenvironment of certain inflammation-related tumours by regulating cancer growth and tumour elimination proved in previou...

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Detalles Bibliográficos
Autores principales: Feng, Wen-Qing, Zhang, Yu-Chen, Xu, Zhuo-Qing, Yu, Su-Yue, Huo, Jian-ting, Tuersun, Abudumaimaitijiang, Zheng, Min-Hua, Zhao, Jing-Kun, Zong, Ya-Ping, Lu, Ai-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200054/
https://www.ncbi.nlm.nih.gov/pubmed/37211606
http://dx.doi.org/10.1186/s12967-023-04187-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200054/
https://www.ncbi.nlm.nih.gov/pubmed/37211606
http://dx.doi.org/10.1186/s12967-023-04187-3

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