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IL-17A-mediated mitochondrial dysfunction induces pyroptosis in colorectal cancer cells and promotes CD8 + T-cell tumour infiltration

BACKGROUND: Interleukin-17A (IL-17A), a proinflammatory cytokine primarily secreted by Th17 cells, γδT cells and natural killer T (NKT) cells, performs essential roles in the microenvironment of certain inflammation-related tumours by regulating cancer growth and tumour elimination proved in previou...

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Detalles Bibliográficos
Autores principales:	Feng, Wen-Qing, Zhang, Yu-Chen, Xu, Zhuo-Qing, Yu, Su-Yue, Huo, Jian-ting, Tuersun, Abudumaimaitijiang, Zheng, Min-Hua, Zhao, Jing-Kun, Zong, Ya-Ping, Lu, Ai-Guo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200054/ https://www.ncbi.nlm.nih.gov/pubmed/37211606 http://dx.doi.org/10.1186/s12967-023-04187-3

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