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Sphingolipids in Cerebrospinal Fluid and Plasma Lipoproteins of APOE4 Homozygotes and Non-APOE4 Carriers with Mild Cognitive Impairment versus Subjective Cognitive Decline

BACKGROUND: Alzheimer’s disease (AD) patients display alterations in cerebrospinal fluid (CSF) and plasma sphingolipids. The APOE4 genotype increases the risk of developing AD. OBJECTIVE: To test the hypothesis that the APOE4 genotype affects common sphingolipids in CSF and in plasma of patients wit...

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Detalles Bibliográficos
Autores principales: den Hoedt, Sandra, Dorst-Lagerwerf, Kristien Y., de Vries, Helga E., Rozemuller, Annemieke J.M., Scheltens, Philip, Walter, Jochen, Sijbrands, Eric J.G., Martinez-Martinez, Pilar, Verhoeven, Adrie J.M., Teunissen, Charlotte E., Mulder, Monique T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200192/
https://www.ncbi.nlm.nih.gov/pubmed/37220621
http://dx.doi.org/10.3233/ADR220072