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Implications of Tau Dysregulation in Huntington’s Disease and Potential for New Therapeutics

Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder. The disease, characterized by motor, cognitive, and psychiatric impairments, is caused by the expansion of a CAG repeat in the huntingtin gene. Despite the discovery of the mutation in 1993, no disease-modifying treatment...

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Detalles Bibliográficos
Autores principales: Mees, Isaline, Nisbet, Rebecca M., Hannan, Anthony J., Renoir, Thibault
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200226/
https://www.ncbi.nlm.nih.gov/pubmed/37092231
http://dx.doi.org/10.3233/JHD-230569