Natural heteroclitic-like peptides are generated by SARS-CoV-2 mutations

Humoral immunity is sensitive to evasion by SARS-CoV-2 mutants, but CD8 T cells seem to be more resistant to mutational inactivation. By a systematic analysis of 30 spike variant peptides containing the most relevant VOC and VOI mutations that have accumulated overtime, we show that in vaccinated an...

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Detalles Bibliográficos
Autores principales: Tiezzi, Camilla, Vecchi, Andrea, Rossi, Marzia, Cavazzini, Davide, Bolchi, Angelo, Laccabue, Diletta, Doselli, Sara, Penna, Amalia, Sacchelli, Luca, Brillo, Federica, Meschi, Tiziana, Ticinesi, Andrea, Nouvenne, Antonio, Donofrio, Gaetano, Zanelli, Paola, Benecchi, Magda, Giuliodori, Silvia, Fisicaro, Paola, Montali, Ilaria, Ceccatelli Berti, Camilla, Reverberi, Valentina, Montali, Anna, Urbani, Simona, Pedrazzi, Giuseppe, Missale, Gabriele, Telenti, Amalio, Corti, Davide, Ottonello, Simone, Ferrari, Carlo, Boni, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200277/
https://www.ncbi.nlm.nih.gov/pubmed/37275517
http://dx.doi.org/10.1016/j.isci.2023.106940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200277/
https://www.ncbi.nlm.nih.gov/pubmed/37275517
http://dx.doi.org/10.1016/j.isci.2023.106940

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