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Potential role of PIM1 inhibition in the treatment of SARS-CoV-2 infection

BACKGROUND: SARS-CoV-2 infection involves disturbing multiple molecular pathways related to immunity and cellular functions. PIM1 is a serine/threonine-protein kinase found to be involved in the pathogenesis of several viral infections. One PIM1 substrate, Myc, was reported to interact with TMPRSS2,...

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Detalles Bibliográficos
Autores principales: Ismail, Magda M. F., El-Awady, Rehab R., Farrag, Amal M., Mahmoud, Sara H., Abo Shama, Noura M., Mostafa, Ahmed, Ali, Mohamed A., Rashed, Mohammed H., Ibrahim, Iman H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200336/
https://www.ncbi.nlm.nih.gov/pubmed/37211584
http://dx.doi.org/10.1186/s43141-023-00520-x