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Novel Mg (2+) binding sites in the cytoplasmic domain of the MgtE Mg (2+) channels revealed by X-ray crystal structures : Structures of the MgtE cytoplasmic domain

MgtE is a Mg (2+)-selective channel regulated by the intracellular Mg (2+) concentration. MgtE family proteins are highly conserved in all domains of life and contribute to cellular Mg (2+) homeostasis. In humans, mutations in the SLC41 proteins, the eukaryotic counterparts of the bacterial MgtE, ar...

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Detalles Bibliográficos
Autores principales: Wang, Mengqi, Zhao, Yimeng, Hayashi, Yoshiki, Ito, Koichi, Hattori, Motoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200709/
https://www.ncbi.nlm.nih.gov/pubmed/37097058
http://dx.doi.org/10.3724/abbs.2023067