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Extracellular histone proteins activate P2XR7 channel current

Extracellular histone proteins are elevated in circulation after injury or activation of the innate immune response. In resistance-size arteries, extracellular histone proteins increased endothelial cell (EC) Ca(2+) influx and propidium iodide (PI) labeling, but paradoxically decreased vasodilation....

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Detalles Bibliográficos
Autores principales: Al-Aqtash, Rua’a, Ross, Maxwell S., Collier, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200710/
https://www.ncbi.nlm.nih.gov/pubmed/37199689
http://dx.doi.org/10.1085/jgp.202213317