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Extracellular histone proteins activate P2XR7 channel current
Extracellular histone proteins are elevated in circulation after injury or activation of the innate immune response. In resistance-size arteries, extracellular histone proteins increased endothelial cell (EC) Ca(2+) influx and propidium iodide (PI) labeling, but paradoxically decreased vasodilation....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200710/ https://www.ncbi.nlm.nih.gov/pubmed/37199689 http://dx.doi.org/10.1085/jgp.202213317 |