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Expression of TMPRSS2 is up-regulated by bacterial flagellin, LPS, and Pam3Cys in human airway cells

Many viruses require proteolytic activation of their envelope proteins for infectivity, and relevant host proteases provide promising drug targets. The transmembrane serine protease 2 (TMPRSS2) has been identified as a major activating protease of influenza A virus (IAV) and various coronaviruses (C...

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Detalles Bibliográficos
Autores principales: Schwerdtner, Marie, Skalik, Annika, Limburg, Hannah, Bierwagen, Jeff, Jung, Anna Lena, Dorna, Jens, Kaufmann, Andreas, Bauer, Stefan, Schmeck, Bernd, Böttcher-Friebertshäuser, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200810/
https://www.ncbi.nlm.nih.gov/pubmed/37208193
http://dx.doi.org/10.26508/lsa.202201813