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Expression of TMPRSS2 is up-regulated by bacterial flagellin, LPS, and Pam3Cys in human airway cells
Many viruses require proteolytic activation of their envelope proteins for infectivity, and relevant host proteases provide promising drug targets. The transmembrane serine protease 2 (TMPRSS2) has been identified as a major activating protease of influenza A virus (IAV) and various coronaviruses (C...
Autores principales: | Schwerdtner, Marie, Skalik, Annika, Limburg, Hannah, Bierwagen, Jeff, Jung, Anna Lena, Dorna, Jens, Kaufmann, Andreas, Bauer, Stefan, Schmeck, Bernd, Böttcher-Friebertshäuser, Eva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200810/ https://www.ncbi.nlm.nih.gov/pubmed/37208193 http://dx.doi.org/10.26508/lsa.202201813 |
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