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Efficacy of puerarin in rats with focal cerebral ischemia through modulation of the SIRT1/HIF-1α/VEGF signaling pathway and its effect on synaptic plasticity

This study aimed to evaluate the efficacy of puerarin and its effect on synaptic plasticity in rats with focal cerebral ischemia (FCI) by modulating the silent mating type information regulation 2 homolog (SIRT1)/hypoxia-inducible factor-1α (HIF-1α)/vascular endothelial growth factor (VEGF) signalin...

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Detalles Bibliográficos
Autores principales: Liu, Xin, Sui, Xiwen, Zhang, Yuqin, Yue, Rongchao, Yin, Shifu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200855/
https://www.ncbi.nlm.nih.gov/pubmed/37223716
http://dx.doi.org/10.1016/j.heliyon.2023.e15872