Axl promotes intracranial aneurysm rupture by regulating macrophage polarization toward M1 via STAT1/HIF-1α

BACKGROUND: Macrophage infiltration and polarization are crucial for the pathogenesis of intracranial aneurysm (IA) rupture. Axl, a receptor tyrosine kinase, is involved in inflammation and efferocytosis in multiple organs. Upregulated soluble Axl in cerebrospinal fluid (CSF) and plasma is correlate...

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Detalles Bibliográficos
Autores principales: Han, Yongquan, Li, Gaozhi, Zhang, Zeyu, Zhang, Xiaohua, Zhao, Bing, Yang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200875/
https://www.ncbi.nlm.nih.gov/pubmed/37223093
http://dx.doi.org/10.3389/fimmu.2023.1158758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200875/
https://www.ncbi.nlm.nih.gov/pubmed/37223093
http://dx.doi.org/10.3389/fimmu.2023.1158758

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