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Integrative single-cell RNA and ATAC sequencing reveals that the FOXO1-PRDX2-TNF axis regulates tendinopathy

INTRODUCTION: Tendinopathy, the most common form of chronic tendon disorder, leads to persistent tendon pain and loss of function. Profiling the heterogeneous cellular composition in the tendon microenvironment helps to elucidate rational molecular mechanisms of tendinopathy. METHODS AND RESULTS: In...

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Detalles Bibliográficos
Autores principales: Guo, Junfeng, Tang, Hong, Huang, Pan, Ye, Xiao, Tang, Chuyue, Shu, Zhao, Kang, Xia, Shi, Youxing, Zhou, Binghua, Liang, Taotao, Tang, Kanglai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200929/
https://www.ncbi.nlm.nih.gov/pubmed/37223090
http://dx.doi.org/10.3389/fimmu.2023.1092778