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Increased meso-striatal connectivity mediates trait impulsivity in FTO variant carriers

OBJECTIVE: While variations in the first intron of the fat mass and obesity-associated gene (FTO, rs9939609 T/A variant) have long been identified as a major contributor to polygenic obesity, the mechanisms underlying weight gain in risk allele carriers still remain elusive. On a behavioral level, F...

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Detalles Bibliográficos
Autores principales: Edwin Thanarajah, Sharmili, Hanssen, Ruth, Melzer, Corina, Tittgemeyer, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200952/
https://www.ncbi.nlm.nih.gov/pubmed/37223038
http://dx.doi.org/10.3389/fendo.2023.1130203