Mature primary human osteocytes in mini organotypic cultures secrete FGF23 and PTH1-34-regulated sclerostin

INTRODUCTION: For decades, functional primary human osteocyte cultures have been crucially needed for understanding their role in bone anabolic processes and in endocrine phosphate regulation via the bone-kidney axis. Mature osteocyte proteins (sclerostin, DMP1, Phex and FGF23) play a key role in va...

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Detalles Bibliográficos
Autores principales: Knowles, Helen J., Chanalaris, Anastasios, Koutsikouni, Argyro, Cribbs, Adam P., Grover, Liam M., Hulley, Philippa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200954/
https://www.ncbi.nlm.nih.gov/pubmed/37223031
http://dx.doi.org/10.3389/fendo.2023.1167734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200954/
https://www.ncbi.nlm.nih.gov/pubmed/37223031
http://dx.doi.org/10.3389/fendo.2023.1167734

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