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Role of enterocyte Enpp2 and autotaxin in regulating lipopolysaccharide levels, systemic inflammation, and atherosclerosis

Conversion of lysophosphatidylcholine to lysophosphatidic acid (LPA) by autotaxin, a secreted phospholipase D, is a major pathway for producing LPA. We previously reported that feeding Ldlr(−/−) mice standard mouse chow supplemented with unsaturated LPA or lysophosphatidylcholine qualitatively mimic...

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Detalles Bibliográficos
Autores principales: Chattopadhyay, Arnab, Mukherjee, Pallavi, Sulaiman, Dawoud, Wang, Huan, Girjalva, Victor, Dorreh, Nasrin, Jacobs, Jonathan P., Delk, Samuel, Moolenaar, Wouter H., Navab, Mohamad, Reddy, Srinivasa T., Fogelman, Alan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200992/
https://www.ncbi.nlm.nih.gov/pubmed/37059333
http://dx.doi.org/10.1016/j.jlr.2023.100370