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Loss of threonyl-tRNA synthetase-like protein Tarsl2 has little impact on protein synthesis but affects mouse development

Aminoacyl-tRNA synthetases (aaRSs) are essential components for mRNA translation. Two sets of aaRSs are required for cytoplasmic and mitochondrial translation in vertebrates. Interestingly, TARSL2 is a recently evolved duplicated gene of TARS1 (encoding cytoplasmic threonyl-tRNA synthetase) and repr...

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Detalles Bibliográficos
Autores principales: Zeng, Qi-Yu, Zhang, Fan, Zhang, Jian-Hui, Hei, Zhoufei, Li, Zi-Han, Huang, Meng-Han, Fang, Pengfei, Wang, En-Duo, Sun, Xiao-Jian, Zhou, Xiao-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200997/
https://www.ncbi.nlm.nih.gov/pubmed/37059185
http://dx.doi.org/10.1016/j.jbc.2023.104704